Neural Plasticity After Spinal Cord Injury

Keratan sulfate restricts neural plasticity after spinal cord injury.

Chondroitin sulfate (CS) proteoglycans are strong inhibitors of structural rearrangement after injuries of the adult CNS. In addition to CS chains, keratan sulfate (KS) chains are also covalently attached to some proteoglycans. CS and KS sometimes share the same core protein, but exist as independent sugar chains. However, the biological significance of KS remains elusive. Here, we addressed th...

Training-Specific Neural Plasticity in Spinal Reflexes after Incomplete Spinal Cord Injury

The neural plasticity of spinal reflexes after two contrasting forms of walking training was determined in individuals with chronic, motor-incomplete spinal cord injury (SCI). Endurance Training involved treadmill walking for as long as possible, and Precision Training involved walking precisely over obstacles and onto targets overground. Twenty participants started either Endurance or Precisio...

Locomotion and Motor Neuron Plasticity after Incomplete Spinal Cord Injury

P24: Neural Stem/Progenitor Cells Treatment for Spinal Cord Injury

لطفاً به چکیده انگلیسی مراجعه شود.

Thermostabilized chondroitinase ABC Promotes Neuroprotection after Contusion Spinal Cord Injury

Background: Chondroitinase ABC (cABC), due to its loosening impact on the extracellular matrix scaffold, has been used to enhance regeneration of injured axonal tracts after spinal cord injury (SCI). However, cABC thermal instability at physiological temperature has limited its clinical application. The disaccharide trehalose has been shown to increase the stability of cABC in body temperature....